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For more than 40 years, there has been a strong partnership between the University of Kentucky College of Medicine and St. Claire HealthCare (SCH), allowing many medical students and residents to rotate through SCH in internal medicine, surgery, pathology, family and community medicine. SCH is proud to serve as an established training site for the University of Kentucky College of Medicine's physician residency programs.

In 2005, SCH and the University of Kentucky Chandler Medical Center agreed to pursue defined affiliations focused on specific areas including cardiology, obstetrics and oncology, as well as other potential clinical areas, and education. By putting in place distinct formalized affiliation agreements for each of the selected clinical areas, collaborations are significantly accelerated. In addition to the immediate expansion of on-site offerings of specialized programs and services, these collaborations enable SCH to access the many resources of the university, which greatly enhances SCH's clinical program development efforts.